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The rapid advances in recombinant DNA technology and the increasing availability of peptides and proteins with therapeutic potential are a challenge for pharmaceutical scientists who have to formulate these compounds as drug products.

Pharmaceutical Formulation Development of Peptides and Proteins, Second Edition discusses the development of therapeutic peptides and proteins, from the production of active compounds via basic pre-formulation and formulation to the registration of the final product.

Providing integrated solutions, this book discusses:

• The synthesis of peptides and the biotechnological production of proteins through recombinant DNA technology
• The physicochemical characteristics and stability of peptides and proteins
• The formulation of proteins as suspensions, solutions, and (mostly freeze-dried) solids
• The opportunities and challenges of non-parenteral delivery of peptides and proteins
• Risk factors, specifically the development of an unwanted immune response
• A simulation approach to describe the fate of peptides and proteins upon administration to a biological system
• The documentation required to register a protein-based drug

Scientists in the pharmaceutical industry and academia as well as postgraduate students in pharmaceutical science will find this a valuable resource.

• Sales Rank: #2459458 in Books
• Published on: 2012-11-14
• Original language: English
• Number of items: 1
• Dimensions: 9.20" h x .90" w x 6.20" l, 1.55 pounds
• Binding: Hardcover
• 392 pages

About the Author

Lars Rovgaard is Principal Scientist for NovoNordisk A/S and a Professor at Copenhagen University, Denmark.

Sven Frokjaer is Dean of the Pharmaceutical Sciences Faculty at the University of Copenhagen Denmark. Marco van de Weert is an Associate Professor of Pharmaceutics and Analytical Chemistry at the University of Copenhagen.

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0 of 0 people found the following review helpful.
Four Stars
By Yu-Nan Liu
Helpful to me

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Tagging is fast becoming one of the primary ways people organize and manage digital information. Tagging complements traditional organizational tools like folders and search on users desktops as well as on the web. These developments mean that tagging has broad implications for information management, information architecture and interface design. And its reach extends beyond these technical domains to our culture at large. We can imagine, for example, the scrapbookers of the future curating their digital photos, emails, ticket stubs and other mementos with tags. This book explains the value of tagging, explores why people tag, how tagging works and when it can be used to improve the user experience. It exposes tagging's superficial simplicity to reveal interesting issues related to usability, information architecture, online community and collective intelligence.

• Sales Rank: #1381182 in Books
• Published on: 2008-01-06
• Released on: 2007-12-27
• Original language: English
• Number of items: 1
• Dimensions: 8.95" h x .43" w x 7.00" l, .75 pounds
• Binding: Paperback
• 216 pages

From the Back Cover
Tagging is fast becoming one of the primary ways people organize and manage digital information. Tagging complements traditional organizational tools like folders and search on users desktops as well as on the web. These developments mean that tagging has broad implications for information management, information architecture and interface design. And its reach extends beyond these technical domains to our culture at large. We can imagine, for example, the scrapbookers of the future curating their digital photos, emails, ticket stubs and other mementos with tags. This book explains the value of tagging, explores why people tag, how tagging works and when it can be used to improve the user experience. It exposes tagging's superficial simplicity to reveal interesting issues related to usability, information architecture, online community and collective intelligence.

About the Author
Gene Smith is a consultant specializing in information architecture strategy, social classification like tagging and folksonomies, emergent information architecture and interaction design. As a principal at nForm User Experience, he's advised clients like Comcast, Ancestry.com and the Canadian Patient Safety Institute. Through conference presentations and online publication Gene has helped define social information architecture, an emerging field that looks at how user interactions create structure in information spaces.

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13 of 15 people found the following review helpful.
Tagging is a new form of information management that relates to personal organization, info architecture, and online communities
By Jeff Lippincott
This was a really good book. It wasn't what I expected it to be. But it was a worthwhile read. I picked it up because I do a fair amount of work writing book reviews and making guides and booklists on Amazon. And Amazon now lets guys like me create tags for the books I review and include in guides and lists. I kind of expected this book would have talked a little bit about the Amazon system of tagging. Nope. But that's OK. It's still a good book. It includes seven chapters and three appendices:

1. What is tagging?
2. The value of tagging
3. Tagging system architecture
4. Tags, metadata, and classical systems
5. Navigation and visualization
6. Interfaces
7. Technical design
A. Case study: social bookmarking
B. Case study: media sharing
C. Case study: personal information management

Tagging is a form of information that is really starting to take root in our computer systems and online systems. I first experienced it back in 1998 when I purchased a copy of Lotus Organizer to use as my Personal Information Manager (PIM) when practicing law. The program allowed me to cross-reference the many lists I had created in its database. I thought it was really cool back then.

I was just getting into creating Web sites in 1998, too. And I found the tagging features in Lotus Organizer enabled me to do with the data in my database what I was doing with my Web pages in my Web sites. Basically tagging is another name for hyperlinking. Nothing more and nothing less. A tag will take you to a new idea, concept, data item, data page, or database. It's a springboard that will take you to information.

This book points out that tagging is a new form of information management as it relates to personal organization, information architecture, and online communities. I suppose my Lotus Organizer program is an example of the first, and Amazon's system is an example of the last. So is it really all that new?

All in all, this book explains the value of tagging. It's a guide to what, how and why to tag. Each chapter ended in a list of bullet points called a Summary. I liked this feature very much since it helped me skim through the book quickly. 5 stars!

6 of 7 people found the following review helpful.
Tagging helps create community
By Paul A. Baker
Participating in a community, sharing our interests, and contributing to the collective good are all fundamentally human motivations, Smith says, and social tagging systems tap into these.

If you use the Web a lot, the stream of information you navigate sometimes seems like a tsunami. Besides emails and RSS feeds, your digital stream can include social networking sites, photos from your friends, links from Del.icio.us, and Twitter tweets.

Tagging these online resources can help you make sense of your stream. If you use tags now, this book will show you ways to juice your game, and will likely point you to new resources. If you don't use tags, this book explains how tagging can help, and how to get started.

And if you're a web architect, Gene Smith walks you through the things you should consider when designing tagging system.

2 of 2 people found the following review helpful.
Exceptional book
By atmj
I have worked on a variety of applications and have participated in conferences where it is clear we all have an incredible amount of data to manage.
It seems tagging is the new means of organizing your data, but it is also equally clear to most of us that this feels very unstructured.

This book is sure to be a seminal book, discussing the early years of tagging. It deals with the basics:
a. What it is
b. Why we want to do it
c. Some various methods and structures for tagging and how we would use it.
d. Examples of the components of tagging, why and where to use them
e. Some code nuts and bolts of how to approach tagging.

Finally there are some real life examples
1. Social bookmarking
2. Media sharing
3. Personal information management.

This book is easy to read and quickly gets you up to speed on some of the issues associated with tagging.

Essentially it says, you need to decide what you want to do, before deciding on the type of tagging you would use.

It also clearly leaves the reader realizing this is just the beginning..

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• Sales Rank: #4792937 in Books
• Published on: 1979-09-20
• Original language: English
• Number of items: 1
• Dimensions: 7.09" h x 4.72" w x .0" l, .38 pounds
• Binding: Paperback
• 150 pages

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The poetry of Sappho, who was born around 620 BC and lived on the Greek island of Lesbos, has inspired and fascinated readers and poets for two and a half thousand years. Today, as in antiquity, she is regarded as Greece's supreme lyric poet. Yet apart from a few near-complete poems, her poetry survives largely in tantalizing fragments. This book traces Sappho's reception in English-language poetry through translations and poems about her. From Donne and Pope via Swinburne, Bliss Carman and Pound to contemporary poets such as Michael Longley and Olga Broumas, it both celebrates and illustrates our changing image of Sappho. Peter Jay edited The Greek Anthology for Penguin Classics. He is the author of a collection of poems, Shifting Frontiers, and has translated some modern Romanian and Hungarian poetry. Caroline Lewis is a writer and lecturer specializing in women's writing and history. She has lived and worked in London and Hong Kong and now lives in Edinburgh.

• Sales Rank: #2259747 in Books
• Brand: Brand: Anvil Press Poetry
• Published on: 2004-06-01
• Original language: English
• Number of items: 1
• Dimensions: 8.50" h x .40" w x 5.40" l, .40 pounds
• Binding: Paperback
• 144 pages

Features

• Used Book in Good Condition

Review
'Sappho Through English Poetry' is a brilliant idea - You find you're following English poetry over four centuries through the prism of two Greek poems, like a CD of Callas, Joan Sutherland, Piaf, Billie Holiday, Bjork and the Spice Girls all singing the same song.' - Ruth Padel, The Observer'What this collection achieves is a commentary on our own literary history, rather than simply a nod to a great classical poet.' - Jane Holland, Poetry Review

About the Author
Peter Jay is a poet who has translated a variety of ancient and modern poets, including Nerval, Pilinszky, Blandiana and Stanescu. He edited The Greek Anthology (Penguin, 1973). He is the editorial director of Anvil Press.

Caroline Lewis is a writer and lecturer specializing in women's writing and history. 

Most helpful customer reviews

0 of 0 people found the following review helpful.
SERIOUS.
By Kohtaro Hayashi
Sappho: Through English Poetry. Edited by Peter Jay & Caroline Lewis. 2001

The first edition was issued in 1996.

The introduction = treatise is a little longer, but very informative. Editors show all about Sappho with the relation between she and English poets deeply.
Through English Poetry, saying in conclusion, it makes us to know that the translation in English has a limitation to express Sappho's poems for which correspond to 'Sappho's wonderful ear'.

But in this book, the good taste "as the poems" are many existing. Without saying, John Donne's, A.C.Swinburne's, Bliss Carman's, and so on.
Particularly in the part one, Peter Whigham's work is individual. His fluent musicality is distinguished. Also, if there were Josephine Balmer's and Diane J Rayor's, it would be the better.
On the whole, this book has accomplished for its purpose.

0 of 0 people found the following review helpful.
Save your money
By eej
Nothing in this book is particularly interesting or useful--unless you really want to read a whole lot of attempted translations by poets who really only try to promote themselves.

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